THE NASAL ELEMENT IN SPASMODIC ASTHMA

The Rôle of the Eosinophiles in the Diagnosis of Spasmodic Asthma

Sputum.?Eosinophils were first noted in the sputum of asthmatics in 1889 by Yon Muller and by Gollasch. In 1892 Aranson and Phillip found that 66 per cent of the cells in the sputum of a patient with asthma were 'eosinophiles. Weiss (1891), Lewy (1900), Heineke and Deutschmann (1906), and Yon Strumpell (1908) found eosinophiles in the sputum in cases other than asthma and considered that the pr...

Nasal CPAP in nonapneic nocturnal asthma.

Nasal CPAP has been shown to improve nocturnal asthma in those patients with associated sleep apnea. We studied seven nonapneic, nonsnoring asthmatics to determine the effect of CPAP in this patient population. On the CPAP night vs the baseline night, there was a significant worsening of sleep architecture. This included increased awake time and decreased REM sleep. For the group, the overnight...

Haemopoietic mechanisms in nasal polyposis and asthma.

Recent studies of the involvement of the bone marrow in human atopic asthmatic responses to inhaled allergen confirm what we have found in a canine model of Ascaris suum induced bronchial hyperresponsiveness: CD34/45+ haemopoietic progenitors, increased in numbers in the blood and marrow of atopic individuals, can be specifically upregulated following airway allergen challenge eliciting bronchi...

Investigation and Conservative Treatment of the Nasal Factor in Asthma

Finite element analysis of airflow in the nasal valve.

We digitized the outline of the nasal cavity from images obtained after applying contrast material to the nose. A computer-aided simulation of flow was undertaken in the sagittal plane in the anterior nasal cavity. Previous work on the nasal valve was reviewed. Our results showed that the nasal valve is an oblique structure bounded laterally by the caudal end of the upper lateral cartilage, med...